Pilot Awards 2012-2013

Jose Aleman, MD, PhD
Breslow Laboratory
Reversal of obesity-associated inflammation and crown-like structures with acute weight loss


Louis Cohen, MD
Brady Laboratory
Metagenomic analysis of bacterial natural products and their role in the intestinal microbiome


Amir Shlomai, MD, PhD
Rice Laboratory
Identifying essential host factors in hepatitis B virus life cycle by modeling infection in hepatocyte-like inducible pluripotent stem cells (iHLCs)


Manish Ponda, MD
Breslow Laboratory
The effect of oral vitamin D vs. ultraviolet light on cholesterol


Jeanne Walker, RN
Center for Clinical and Translational Science
The effects of trans-resveratrol on insulin resistance, inflammation, and the metabolic syndrome: a placebo controlled, double blind study


Juana Gonzalez, PhD
Translational Technology Core Laboratory
A Pilot Study to characterize adipose tissue leukocytes by flow cytometry and microscopy in lean, obese, and psoriatic subjects


Roos Karssemeljer
Mucida Laboratory
The influence of the microbiota on epigenetic regulation of gene expression in intestinal lymphocytes


Ype De Jong, MD, PhD
Rice Laboratory
Identification of factors that enhance human FLPC and iHLC engraftment in mice.


Naglaa Shoukry, PhD
Rice Laboratory
Pilot transcriptome analysis of acute HCV


Brad Rosenberg, MD, PhD
Presidential Whitehead Fellow
Immune profiling by high throughput sequencing of complete antigen receptors


Darren Ruane, PhD
Nussenzweig Laboratory
Generation of gut-homing IgA-secreting B cells by lung resident Dendritic cells


Thomas P. Sakmar, MD
Sakmar Laboratory
Novel Anti-amyloid therapy for type 2 diabetes mellitus using conformation-specific antiprotofibril monoclonal antibodies


Sanford Simon, PhD
Simon Laboratory
Live cell imaging of Hepatitis C virus assembly and release


Sanford Simon, PhD
Simon Laboratory
Live cell imaging of hepatic lipoprotein assembly and release, and their interaction with Hepatitis C virus


C. Erec Stebbins, PhD
Stebbins Laboratory
Studies of the bacterial Oncoprotein CagA bound to the human tumor suppressor ASPP2


Gaelle Breton, PhD
Nussenzweig Laboratory
Characterization of intestinal dendritic cell subsets in human for the rational design of mucosal vaccine strategies.


Sohail Tavazoie, MD, PhD
Tavazoie Laboratory
In vivo delivery of microRNAs for treatment of colorectal cancer metastasis


Alexander Nguyen, MD, PhD
Tavazoie Laboratory
Therapeutic inhibition of autocrine signaling pathways involved in colorectal cancer metastasis